La maladie de Parkinson au Canada (serveur d'exploration)

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Serum antioxidant enzyme activity in Parkinson's disease

Identifieur interne : 004551 ( Main/Exploration ); précédent : 004550; suivant : 004552

Serum antioxidant enzyme activity in Parkinson's disease

Auteurs : Jawahar Kalra [Canada] ; Ali H. Rajput [Canada] ; Subrahmanyam V. Mantha [Canada] ; Kailash Prasad [Canada]

Source :

RBID : ISTEX:14A72AB060514FBBD853FA1FFCC3898997C5C910

Descripteurs français

English descriptors

Abstract

Summary: The activities of superoxide dismutase (SOD; EC 1.15.1.1) and glutathione peroxidase (GSHPx; EC 1.11.1.9.), the enzymes that metabolize the superoxide anion and hydrogen peroxide, respectively, were measured in serum from healthy subjects and patients with Parkinson's disease (PD). The activities of SOD and GSHPx in patients with PD were higher than those in normal healthy individuals. These results suggest that the increased activities of these enzymes could be due to oxidative stress in the initial stages of this disease.

Url:
DOI: 10.1007/BF02454194


Affiliations:


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<div type="abstract" xml:lang="en">Summary: The activities of superoxide dismutase (SOD; EC 1.15.1.1) and glutathione peroxidase (GSHPx; EC 1.11.1.9.), the enzymes that metabolize the superoxide anion and hydrogen peroxide, respectively, were measured in serum from healthy subjects and patients with Parkinson's disease (PD). The activities of SOD and GSHPx in patients with PD were higher than those in normal healthy individuals. These results suggest that the increased activities of these enzymes could be due to oxidative stress in the initial stages of this disease.</div>
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