Serum antioxidant enzyme activity in Parkinson's disease
Identifieur interne : 004551 ( Main/Exploration ); précédent : 004550; suivant : 004552Serum antioxidant enzyme activity in Parkinson's disease
Auteurs : Jawahar Kalra [Canada] ; Ali H. Rajput [Canada] ; Subrahmanyam V. Mantha [Canada] ; Kailash Prasad [Canada]Source :
- Molecular and Cellular Biochemistry [ 0300-8177 ] ; 1992-03-01.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Antioxidants (metabolism), Enzymatic activity, Exploration, Female, Glutathione Peroxidase (blood), Glutathione peroxidase, Human, Humans, Male, Middle Aged, Parkinson Disease (blood), Parkinson Disease (enzymology), Parkinson disease, Pathogenesis, Pathophysiology, Serum, Superoxide Dismutase (blood), Superoxide dismutase.
- MESH :
- chemical , blood : Glutathione Peroxidase, Superoxide Dismutase.
- chemical , metabolism : Antioxidants.
- blood : Parkinson Disease.
- enzymology : Parkinson Disease.
- Aged, Female, Humans, Male, Middle Aged.
Abstract
Summary: The activities of superoxide dismutase (SOD; EC 1.15.1.1) and glutathione peroxidase (GSHPx; EC 1.11.1.9.), the enzymes that metabolize the superoxide anion and hydrogen peroxide, respectively, were measured in serum from healthy subjects and patients with Parkinson's disease (PD). The activities of SOD and GSHPx in patients with PD were higher than those in normal healthy individuals. These results suggest that the increased activities of these enzymes could be due to oxidative stress in the initial stages of this disease.
Url:
DOI: 10.1007/BF02454194
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Summary: The activities of superoxide dismutase (SOD; EC 1.15.1.1) and glutathione peroxidase (GSHPx; EC 1.11.1.9.), the enzymes that metabolize the superoxide anion and hydrogen peroxide, respectively, were measured in serum from healthy subjects and patients with Parkinson's disease (PD). The activities of SOD and GSHPx in patients with PD were higher than those in normal healthy individuals. These results suggest that the increased activities of these enzymes could be due to oxidative stress in the initial stages of this disease.</div>
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